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20-(tert-Butoxy)-20-oxoicosanoic acid

CAS No. 683239-16-9

20-(tert-Butoxy)-20-oxoicosanoic acid( —— )

Catalog No. M28903 CAS No. 683239-16-9

20-(tert-Butoxy)-20-oxoicosanoic acid is a alkyl-chain-based PROTAC linker. 20-(tert-Butoxy)-20-oxoicosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    20-(tert-Butoxy)-20-oxoicosanoic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    20-(tert-Butoxy)-20-oxoicosanoic acid is a alkyl-chain-based PROTAC linker. 20-(tert-Butoxy)-20-oxoicosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
  • Description
    20-(tert-Butoxy)-20-oxoicosanoic acid is a alkyl-chain-based PROTAC linker. 20-(tert-Butoxy)-20-oxoicosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
  • In Vitro
    ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    GABA Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    683239-16-9
  • Formula Weight
    398.628
  • Molecular Formula
    C24H46O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)(C)OC(=O)CCCCCCCCCCCCCCCCCCC(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Manev H, et al. Progabide, a GABA mimetic drug, stimulates the secretion of plasma corticosterone in rats. Pharmacol Biochem Behav. 1987 Dec;28(4):443-6.
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